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Immuno cytochemistry of heat shock proteins HSP70 in pig liver after a parasitic invasion

ANTALIKOVA L, KOUBKOVA M, ROZINEK J, JILEK F
Veterinarni Medicina 45, 2000, 5-11

The presence of heat shock proteins 70 (HSP70) in pig liver tissue was detected using the immunocytochemical method as a response to the stress represented by parasitic invasion (Ascaridae). An increased occurrence of HSP70 was detected in the cytoplasm of hepatocytes in the close vicinity of the vena centralis. After using the antibody anti-HSP70 a positive reaction was detected in the nuclei of the hepatocytes in certain areas of the liver. A strong reaction was observed in the cytoplasm of cells forming necrotic foci. Multiplied connective tissue was plentifully infiltrated by eosinophilic granulocytes, which also demonstrated positivity. A slight positive reaction was also present in the endothelial cells of blood vessels as well as in the multiplied Kupffer cells


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