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PAPER SELECTED

The Effect of Fungal and Yeast Glucan and Levamisole on the Level of Cellular Immune-Response Invivo and Phagocyte Activity of Blood Leukocytes in Mice

PAULIK S, SVRCEK S, HUSKA M, MOJZISOVA J, DUROVE A, BENISEK Z
Veterinarni Medicina 37, 1992, 675-685

The level of cell-mediated immune response in vivo was investigated using the test of delayed hypersensitive reaction (DHR) to DNFB, along with the phagocytic activity (PA) of blood leucocytes in mice after subcutaneous implantation of fungal and yeast glucan and levamisol in dependence on the dose and administration schedule. The soluble form of fungal glucan (Pleurotus ostreatus) potentiated the DHR significantly at a dose of 10 mg/kg (but not at a dose of 50 mg/kg) while it was administered during DNFB sensitization (P<0.05) - Tab. I and when its pre-medication effect was investigated (days -7 and -14


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